Resistance to epigenetic-targeted therapy engenders tumor cell vulnerabilities associated with enhancer remodeling
Iniguez AB, Alexe G, Wang EJ, Roti G, Patel S, Chen L, Kitara S, Conway A, Robichaud AL, Stolte B, Bandopadhayay P, Goodale A, Pantel S, Lee Y, Cheff DM, Hall MD, Guha R, Davis MI, Menard M, Nasholm N, Weiss WA, Qi J, Beroukhim R, Piccioni F, Johannessen C, Stegmaier K
Cancer Cell (2018): December 10. doi:10.1016/j.ccell.2018.11.005.[Epub ahead of print]
Old meets new-the path to combination treatments in pediatric low-grade gliomas
Clymer J, Bandopadhayay P
Neuro Oncol (2018): December 11. doi:10.1093/neuonc/noy188. [Epub ahead of print]
Management of pediatric low-grade glioma
de Blank P, Bandopadhayay P, Haas-Kogan D, Fouladi M, Fangusaro J
Curr Opin Pediatric (2018): Dec 3. doi:10.1097/MOP.0000000000000717 [Epub ahead of print]
Genetic and transcriptional evolution alters cancer cell line drug response
Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, O’Rourke R, Garrity A, Tubelli AA, Bandopadhayay P, Tsherniak A, Vazquez F, Wong B, Birger C, Ghandi M, Thorner AR, Bittker JA, Meyerson M, Getz G, Beroukhim R, Golub TR.
Nature (2018): August 8. doi:10.1038/s41586-018-0409-3 [Epub ahead of print]
Dual HDAC and PI3K inhibition abrogates NFkB- and FOXM1-mediated DNA damage response to radiosensitize pediatric high-grade gliomas.
Pal S, Kozona D, Yang X, Fendler W, Fitts W, Ni J, Alberta JA, Zhao J, Liu KX, Bian J, Truffaux N, Weiss WA, Resnick AC, Bandopadhayay P, Ligon KL, Dubois SG, Mueller S, Chowdhury D, Haas-Kogan DA
Cancer Res (2018): May 14. doi:10.1158/0008-5472.CAN-17-3691 [Epub ahead of print]
Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.
Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Geyer JR, Leary S, Browd S, Wang Z, Sood S, Bendel A, Nagib M, Gardner S, Karajannis MA, Harter D, Ayyanar K, Gump W, Bowers DC, Weprin B, MacDonald TJ, Aguilera D, Brahma B, Robison NJ, Kiehna E, Krieger M, Sandler E, Aldana P, Khatib Z, Ragheb J, Bhatia S, Mueller S, Banerjee A, Bredlau AL, Guruangan S, Fuchs H, Cohen KJ, Jallo G, Dorris K, Handler M, Comito M, Dias M, Nazemi K, Baird L, Murray J, Lindeman N, Hornick JL, Malkin H, Sinai C, Greenspan L, Wright KD, Prados M, Bandopadhayay P, Ligon KL, Kieran MW
Neuro Oncol (2018): May 5. doi 10.1093/neuonc/noy070 [Epub ahead of print]
Case-base review:pediatric medulloblastoma
Kline CN, Packer RJ, Hwang EI, Raleigh DR, Braunstein S, Raffel C, Bandopadhayay P, Solomon DA, Aboian M, Cha S, Mueller S
Neurooncol Pract (2017): Sep;4(3):138-150.
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.
Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popovic M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fristch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suva ML
Science (2018): Apr 20;360(6386):331-335.
Landscapes of childhood tumours.
Bandopadhayay P, Meyerson M
Nature. 2018 Mar 15; 555(7696):316-317
SvABA: genome-wide detection of structural variants and indels by local assembly.
Wala JA, Bandopadhayay P, Greenwald N, O’Rourke R, Sharpe T, Stewart C, Schumacher S, Li Y, Weischenfeldt J, Yao X, Nusbaum C, Campbell P, Getz G, Meyerson M, Zhang CZ, Imielinski M, Beroukhim R
Genome Res. 2018 Mar 13. doi 10.1101/gr.221028.117. [Epub ahead of print]
Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response.
Plant, Ashley S., Shohei Koyama, Claire Sinai, Isaac H. Solomon, Gabriel K. Griffin, Keith L. Ligon, Pratiti Bandopadhayay, Betensky R, Emerson R, Dranoff G, Kieran MW, Ritz, J
Journal of neuro-oncology (2018): 1-10.