Advances in the classification and treatment of pediatric brain tumors
Fangusaro J and Bandopadhayay P
Curr Opin Pediatr. 2020 Dec 4. doi:10.1097/MOP.000975
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
Chen CCL, Deshmukh S, Jessa S, Hadjadj D, Lisi V, Andrade AF, Faury D, Jawhar W, Dali R, Suzuki H, Pathania M, Deli A, Dubois F, Woodward E, Hebert S, Coutelier M, Karamchandani J, Albrecht S, Brandner S De Jay N, Gayden T, Bajic A, Harutyunyan AS, Marcchione DM, Mikael LG, Juretic N, Zeineh M, Russo C, Maestro N, Bassenden AV, Hauser P, Virga J, Bognar L, Klekner A, Zapotocky M, Vicha A, Krskova L, Vanova K, Zamecnik J, Sumerauer D, Ekert PG, Ziegler DS, Ellezam B, Filbin MG, Blanchette M, Hansford JR, Khuong-Quang DA, Berghuis AM, Weil AG, Garcia BA, Garzia L, Mack SC, Beroukhim R, Ligon KL, Taylor MD, Bandopadhayay P, Kramm C, Pfister SM, Korschunov A, Sturm D, Jones DTW, Salomoni P, Kleinman CL, Jabado N
Cell (2020); S0092-8674(20)31529-4 doi:10.1016/j.cell.2020.11.012
CloneSifter: enrichment of rare clones from heterogenous cell populations
Feldman D, Tsai FN, Garrity AJ, O’Rourke R, Brenan L, Ho, P, Gonzalez E, Konermann S, Johannessen C#, Beroukhim R#, Bandopadhayay P#, Blainey PC#
BMC Biology (2020); Nov 24;18(1):177. doi:10.1186/s12915-020-00911-y3
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
PCAWG Consortium
Nature Commun (2020); Sept 21;11(1):4748. doi:10.1038/s41467-020-18151-y
Sex differences in oncogenic mutational processes
PCAWG Consortium
Nature Commun (2020); Aug 28;11(1):4330. doi:10.1038/s41467-020-17359-2
Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma
Manoharan N, Choi J, Chordas C, Zimmerman MA, Scully J, Clymer J, Filbin M, Ullrich NJ, Bandopadhayay P, Chi SN, Yeo KK
J Neuro-Onc (2020); Sept;149(2):253-262. doi:10.1007/s11060-020-03952
Mechanisms and therapeutic implications of hypermutation in gliomas
Touat M*, Li YY*, Boynton AN, Spurr LF, Iorgulescu JB, Bohrson CL, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ, Pal S, Ferrer-Luna R, Ramkissoon SH, Dubois F, Bellamy C, Currimjee N, Bonardi J, Qian K, Ho P, Malinowski S, Taquet L, Jones RE, Shetty A, Chow KH, Sharaf R, Pavlick D, Albacker LA, Younan N, Baldnin C, Verreault M, Giry M, Guillerm E, Ammari S, Beuvon F, Mokhtari K, Alentorn A, Dehais C, Houillier C, Laigle-Donadey F, Psimaras D, Lee EQ, Nayak L, McFaline-Figueroa JR, Carpentier A, Cornu P, Capelle L, Mathon B, Barnholtz-Sloan JS, Chakravarti A, Bi WL, Chiocca EA, Fehnel KP, Alexandrescu S, Chi SN, Haas-Kogan D, Batchelor TT, Frampton GM, Alexander BM, Huang RY, Ligon AH, Coulet F, Delattre YV, Hoang-Xuan K, Meredith DM, Wen PY, Reardon DA, Marabelle A, Park PJ, Idbaih A, Beroukhim R#, Bandopadhayay P#, Bielle F# & Ligon KL#
Nature (2020) Pub online 15 April 2020. doi: 10.1038/s41586-020-2209-9
The “Risk” in Pediatric Low-Grade Glioma
Fangusaro J and Bandopadhayay P
Cancer Cell (2020); Apr 13;37(4): 424-425. doi:10.1016/j.ccell.2020.03.020.
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
PCAWG Consortium
Nature (2020); 578 (7793): 102-111. doi:10.1038/s41586-020-1965-x.
Pan-cancer Analysis of whole genomes
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Nature (2020); 578 (7793): 82-93. doi:10.1038/s41586-020-1969-6.
Pathway and Network Analysis of more than 2500 whole cancer genomes
PCAWG Consortium
Nature Commun (2020); 11(1):729. Published 2020 Feb 5. doi: 10.1038/s41467-020-14367-0.
Combined burden and functional impact tests for cancer driver discovery using DriverPower
PCAWG Consortium
Nature Commun (2020); 11(1):734. Published 2020 Feb 5. doi: 10.1038/s41467-019-13929-1.
Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway
Kurrpa KJ, Liu Y, To C, Zhang T, Fan M, Vajdi A, Knelson EH, Xie Y, Lim K, Cejas P, Portell A, Lizotte PH, Ficarro SB, Li S, Chen T, Haikala HM, Wang H, Bahcall M, Gao Y, Shalhout S, Boettcher S, Shin BH, Thai T, Wilkens MK, Tillgren ML, Mushajiang M, Xu M, Choi J, Bertram AA, Ebert BL, Beroukhim R, Bandopadhayay P, Awad MM, Gokhale PC, Kirschmeier PT, Marto JA, Camargo FD, Haq R, Paweletz CP, Wong KK, Barbie DA, Long HW, Gray NS, Janne PA
Cancer Cell (2020) Jan 13; 37(1):104-122.e12. doi: 10.1016/j.ccell.2019.12.006